Coelenterazine (native)

Marka :

Katalog No : 10110, 10110-1, 10110-2

Product Description

Coelenterazine (native form) is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. The aequorin complex has been used as an excellent calcium indicator that can measure a broad concentration range of calcium from ~0.1 uM to >100 uM (References 1-4). Renilla luciferase, encoded by the luc gene, has been widely used as a reporter protein. Renilla luciferase/coelenterazine has also been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) (5) to study protein-protein interactions. Other uses of coelenterazine include chemiluminescent detection of superoxide anion and peroxynitrite in cells or tissues (6-9). Biotium also offers Renilla Luciferase Assay Kits () and Firefly & Renilla Dual Luciferase Assay Kits (30005). See the coelenterazine flyer under downloads for a comparison of coelenterazine analogs.

• Yellow solid soluble in MeOH or EtOH
• Store at -20°C and protect from light
• C₂₆H₂₁N₃O_{3MW: 423}
• [55779-48-1]

•  

  Flyer (PDF): Physical Properties of Coelenterazine Analogs

   

  MSDS (PDF): MSDS 10110