MSDS (PDF): MSDS 50015
Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluoronic F-127 (#59004) a mild detergent, is often used as a dispersing agent to facilitate cell loading. Fluo-3 AM ester itself does not bind Ca2+, but it is readily hydrolyzed to fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening.
For information on fluo-3, see #50010.